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The
relationship between performance on cognitive tasks
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and
circulating levels of lead in blood and accumulated
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levels of
lead in bone was examined in 141 middle-aged and
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elderly men.
Men with higher levels of blood and bone
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(tibia)
lead copied spatial figures less accurately; men with
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higher
levels of bone (tibia) lead had slower responses for
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pattern
memory. These findings
suggest that low levels of
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lead contribute to impairments in cognitive function among
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elderly men.
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Payton
M, Riggs KM, Spiro A 3rd, Weiss ST, Hu H Relations of bone
and blood lead to
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cognitive
function: the VA Normative Aging Study.
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Neurotoxicol
Teratol 1998 Jan-Feb;20(1):19-27
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