Dementia and lead 1
v The relationship between performance on cognitive tasks
and circulating levels of lead in blood and accumulated
levels of lead in bone was examined in 141 middle-aged and
elderly men. Men with higher levels of blood and bone
(tibia) lead copied spatial figures less accurately; men with
higher levels of bone (tibia) lead had slower responses for
pattern memory. These findings suggest that low levels of
lead contribute to impairments in cognitive function among
elderly men.
Payton M, Riggs KM, Spiro A 3rd, Weiss ST, Hu H Relations of bone and blood lead to
cognitive function: the VA Normative Aging Study.
Neurotoxicol Teratol 1998 Jan-Feb;20(1):19-27
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